The seventh annual Global Health & Infectious Disease Conference, HIV 2019: Recent Advances and Emerging Trends, will include a panel discussion, poster session, presentations and lunch.
Poster abstracts are due by Friday, February 22nd and can be submitted via this registration form. Applicants will be notified within a week of the abstract deadline.
Registration requested, but not required to attend.
8:00am Check-in, refreshments & poster session
8:40am Ericka Hayes, MD
Global Pediatric HIV: Successes and Challenges
- The current epidemiology of pediatric HIV infection in resource rich and resource limited countries
- Current approaches globally for prevention of mother to child transmission
- The importance of successful suppressive antiretroviral therapy in progress toward ending pediatric cases of HIV
9:15am Liang Shan, PhD
Immunological Approaches to the Clearance of Residual HIV in Patients under Combination Antiretroviral Therapy
- Despite effective combination antiretroviral therapy, HIV-1 persists in a latent form in quiescent memory CD4+ T cells.
- Interleukin-15 drives differentiation of HIV-infected CD4+ T cells into long-lived quiescent memory cells and promotes HIV latency.
- Enhancement of antibody-dependent cellular phagocytosis leads to improved clearance of HIV-infected cells.
9:50am John Santelli, MD, MPH, FAAP, FASHA
Girl’s Access to Education and Declining Teen Fertility, HIV Incidence, and Child Marriage: A Quarter Century of Progress in Rural Uganda
- Access to primary and secondary education has risen over the past 25 years in Rakai, Uganda, as a result of government policy, parental expectations, and rising socioeconomic status.
- Both access to education and HIV prevention programs have contributed to declining HIV risk behaviors and HIV incidence and prevalence.
- Considerable declines in teen fertility and child marriage can also be traced to change in social, education, and health policies and programs
10:25am Break & poster session
10:45am Sebla Kutluay, PhD
The Unexpected Role of HIV-1 Integrase Protein in Virion Maturation
- Integrase binding to the viral RNA genome drives proper particle maturation
- Integrase-RNA interactions are targetable
- Capsid lattice protects vRNPs from degradation in target cells
11:20am Proscovia Nabunya, PhD
Impacts of Economic Strengthening Interventions on AIDS-Impacted Children, Adolescents and their Families in sub-Saharan Africa
- The burden of poverty and HIV/AIDS on children, youth, families and countries at large in sub-Saharan Africa
- The mechanisms and cost of using savings accounts as economic strengthening interventions among these populations
- The effects/benefits of economic strengthening to these populations (children, adolescents, families) regarding educational and health outcomes
11:55am Rupa Patel, MD,MPH DTM&H
Global Oral PrEP Implementation
- The evolution of PrEP policies globally
- Key program implementation models worldwide
- Lessons learned to advance progress in curbing global HIV incidence
12:30pm Panel Discussion
HIV: Where do we go from here
- Ericka Hayes, MD
- George Kyei, MBChB, PhD
- John Santelli, MD, MPH, FAAP, FASHA
- Robert Schooley, MD
2:00pm Poster Session
3:00pm Event Close
Ericka Hayes, MD, Associate Professor Department of Pediatrics, Division of Infectious Diseases, Washington University
In 2005, Hayes joined the Department of Pediatrics as faculty and has served as the medical director of the Washington University Pediatric and Adolescent HIV program for the last 10 years. Dr. Hayes’s past research projects have focused on metabolic complications and drug dosing of HIV medicines in severely malnourished children in Malawi; implementation and optimization of universal HIV testing programs for adolescents and young adults and sexually transmitted infection diagnosis and treatment in high risk youth. She also serves Saint Louis Children’s Hospital as medical director of Infection Prevention.
George Kyei, MBChB, PhD, Department of Medicine, Division of Infectious Diseases, Washington University
Dr. Kyei’s lab at Washington University is focused understanding HIV persistence. Specifically, he is interested in the host factors that enable the virus to persist in patients in the face of anti-retroviral therapy and strong immune pressure. The goal is to identify and characterize therapeutic targets that will be useful for HIV cure.
Sebla Kutluay, PhD, Assistant Professor, Department of Molecular Microbiology, Washington University
Dr. Kutluay’s current research is aimed at the discovery of how viral and cellular RNA-binding proteins regulate HIV-1 replication by employing diverse set of cutting-edge tools. She and her group have published numerous articles in top-ranked scientific journals. She is the recipient of Andy Kaplan Prize in Retrovirology and Andrew and Virginia Craig Faculty Fellowship.
Proscovia Nabunya, PhD, Research Assistant Professor, Brown School, Washington University
Dr. Nabunya’s global research agenda is focused on HIV/AIDS-stigma reduction strategies; family and community-based support systems as protective factors for the development and health well-being of children and families; and poverty-reduction strategies that utilize asset-based interventions for children and families in HIV-impacted communities in sub-Saharan Africa.
Rupa Patel, MD,MPH DTM&H, Assistant Professor, Director, HIV Prevention (PrEP) Program, Department of Medicine, Division of Infectious Diseases, Washington University
Dr. Patel’s research interests include financial and insurance related barriers to PrEP access and retention among young adults in Medicaid non-expansion states. Dr. Patel is a member of the WHO PrEP Implementation Technical Advisory Group and has served as a PrEP clinical advisor and reviewer for projects in Asia, Africa, North America, and South America.
John Santelli, MD, MPH, FAAP, FASHA, Professor, Population and Family Health and Pediatrics, Mailman School of Public Health and College of Physicians and Surgeons, Columbia University
Dr. Santelli has conducted policy-related research on HIV/STD risk behaviors, trends in teen fertility, programs to prevent STD/HIV/unintended pregnancy, school-based health centers, adolescent clinical preventive services, and research ethics. He has been a global leader in ensuring that adolescents have access to medically accurate, comprehensive sexuality education and are appropriately included in health research.
Robert Schooley, MD, Professor of Medicine, Division of Infectious Diseases, Vice Chair, Department of Medicine, Senior Director, International Initiatives, University of California, San Diego
Dr. Schooley began his research career studying the immunopathogenesis of herpesvirus infections in immunocompromised patients, but shifted his focus to AIDS in 1981 when the first cases of this syndrome began to appear in Boston. His research group was among the first to delineate the humoral and cellular immune responses to HIV infection. Over the next 15 years he became increasingly involved in the discovery and development of antiretroviral chemotherapeutic agents including reverse transcriptase inhibitors, protease inhibitors and entry inhibitors. Currently, Dr. Schooley’s personal research interests include HCV, influenza and HIV pathogenesis, and therapy and infections that cause morbidity and mortality in resource limited settings.
Liang Shan, PhD, Assistant Professor, Department of Medicine, Division of Infectious Diseases, Washington University
Dr. Shan completed his PhD training in Dr. Robert Siliciano lab at Johns Hopkins University School of Medicine. His PhD work focused on in vitro models of HIV latency and viral-specific CD8+ T cell responses. He then joined Dr. Richard Flavell lab at Yale University as a postdoc fellow where he worked on developing novel humanized mouse models to study human immune system. Dr. Shan joined Washington University in St. Louis in September 2017. His lab uses humanized mice and patient biopsies to study how immune system respond to HIV-1 infection and how to develop immunotherapeutic strategies to target HIV-1 latent reservoirs.
Parking & directions
Click here for driving and public transit directions.
Upon arriving, please utilize levels 6-7 of the Metro Parking Garage located at the corner of Taylor Avenue and Children’s Place. The address is 4560 Children’s Place, St. Louis, MO 63110. Please note, the Metro Parking Garage only accepts cash.
Event Sponsors: Global Health Center at the Institute for Public Health