- bacterial infection, gastrointestinal disease, global health, herpes simplex virus, HIV & AIDS, infectious disease, norovirus, virology
Dr. Virgin studies mechanisms of immunity and inflammation relevant to inflammatory diseases. His goal is to understand, particularly for chronic infections, how the equilibrium between virus and host operates in molecular and immunologic terms, and how it is disrupted during disease. He focuses on host pathways that are important for human disease susceptibility such as autophagy and interferon responses. His primary interest is in chronic virus infection and the virome, but he also studies bacterial, helminth, and apicomplexan pathogens and commensals as needed to define mechanisms.