- cardiovascular disease, risk factors & disease risk, depression & anxiety, comparative-effectiveness research, outcomes research
The central focus of Dr. Nagele’s group is on cardiac risk of patients undergoing noncardiac surgery. More than two hundred million surgeries are performed each year worldwide. A substantial fraction of these patients will experience a serious cardiac event in the perioperative phase that often negatively affects morbidity and mortality. His goal is to improve understanding of perioperative cardiac events, their diagnosis, prediction, management and prevention.
Dr. Nagele’s second area of interest is the use of nitrous oxide for the treatment of major depression and prevention of suicide in collaboration with the Department of Psychiatry in Washington University School of Medicine in St. Louis.